A PhD studentship is available to study the biological function of prostate-derived sterile 20-like kinases (PSKs), a novel family of protein kinases that act upstream of mitogen-activated protein kinase (MAPK) signalling pathways.
Our recent work has shown that PSKs play important roles in regulating cytoskeletal organisation, gene transcription, stress responses and apoptosis, and the aim of the project is to examine how PSKs regulate cell cycle progression and apoptosis in malignant cells (for further details see JD Morris et al. J. Biol. Chem. (2006) E-pub Dec 11th, J. Biol. Chem. (2006) 281, 7317-, J. Biol. Chem. (2003) 278, 18035- and J. Biol. Chem. (2000) 275, 4311-).
The work will use a wide range of cell and molecular techniques and be based in recently refurbished and well-equipped laboratories located in the Rayne Institute, a dedicated research centre and part of King's College London.
Dr Jonathan Morris and Dr Shaun Thomas will supervise the project.
The position is available for three years and includes a tax-free stipend of £17,000 per annum plus tuition fees paid at the home rate.
Applicants should have a 1st class or 21 Honours degree in a Biological Sciences subject with relevance to Eukaryotic cell and molecular biology.
To apply please send your CV and the names of two referees to Dr Jonathan Morris (E-mail: jonathan.morris [at] kcl.ac.uk).
Follow the links below for more details and application contacts.